| Datum | Heim | Gast | Halle | Ergebnis |
|---|
| 09.10.2021, 17:30 | Pully Lausanne Foxes | Villars Basket | Arnold-Reymond | 76:82 |
| 16.10.2021, 17:30 | Villars Basket | Morges-Saint-Prex Red Devils | CS Platy | 64:85 |
| 22.10.2021, 20:30 | Groupe E Académie Fribourg U23 | Villars Basket | St-Léonard | 86:88 |
| 30.10.2021, 17:30 | Villars Basket | Vevey Riviera Basket | CS Platy | 48:89 |
| 06.11.2021, 17:30 | GC Zürich Wildcats | Villars Basket | Im Birch Zürich | 74:63 |
| 13.11.2021, 18:00 | Villars Basket | BC Bären Kleinbasel | CS Platy | 103:77 |
| 27.11.2021, 17:30 | Villars Basket | Union Lavaux Riviera Basket | CS Platy | 84:66 |
| 04.12.2021, 17:30 | Villars Basket | Goldcoast Wallabies | CS Platy | 69:61 |
| 11.12.2021, 17:30 | Sion Basket | Villars Basket | Creusets | 48:56 |
| 17.12.2021, 20:30 | Centre National du Basket Suisse | Villars Basket | Vallée Jeunesse | 61:83 |
| 07.01.2022, 20:30 | Villars Basket | Pully Lausanne Foxes | CS Platy | 80:70 |
| 15.01.2022, 17:30 | Villars Basket | Sion Basket | CS Platy | 60:47 |
| 23.01.2022, 16:00 | BC Bären Kleinbasel | Villars Basket | Dreirosen Halle | 55:98 |
| 05.02.2022, 17:30 | Vevey Riviera Basket | Villars Basket | Galeries du Rivage | 88:52 |
| 12.02.2022, 17:30 | Villars Basket | GC Zürich Wildcats | CS Platy | 57:81 |
| 26.02.2022, 17:30 | Goldcoast Wallabies | Villars Basket | Allmendli | 72:51 |
| 06.03.2022, 16:00 | Villars Basket | Groupe E Académie Fribourg U23 | CS Platy | 58:90 |
| 13.03.2022, 17:30 | Union Lavaux Riviera Basket | Villars Basket | Galeries du Rivage | 57:66 |
| 18.03.2022, 20:30 | Villars Basket | Centre National du Basket Suisse | CS Platy | 78:71 |
| 26.03.2022, 17:30 | Morges-Saint-Prex Red Devils | Villars Basket | Cherrat | 88:68 |